Hereditary Angioedema

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This fund has been developed in response to patients who have contacted PAF for help with their medication expenses and could not find help. While this fund has been fully designed and we are ready to provide needed support to these patient communities, this fund is not yet able to accept applications for assistance as we are still working to secure charitable donations that will allow us to open it.

If you, or someone you know, would like to contribute to this fund, please visit our Donors page for more information on how to provide critical support for patients in need.

Fund Type

Co-Pay, Co-insurance & Deductible (medications and office visits), Medical Insurance Premiums

Maximum Award Level

$14,000 Per Year

Eligibility Requirements
  • Household Income Requirements 400% or less of Federal Poverty Guideline (FPG) (adjusted for Cost of Living Index (COLI) and number in household)
  • Insurance Requirements All Insurance Types
  • Must reside and receive treatment in the United States.

About Hereditary Angioedema

Hereditary Angioedema (HAE) is a rare genetic primary immunodeficiency characterized by recurrent painful episodes of the accumulation of fluids outside of the blood vessels, caused by a mutation in the C1NH gene in the blood. The swelling blocks the normal flow of blood or lymphatic fluid causing temporary swelling of tissues in 3 parts of the body: the skin – the face, hands legs, genitals and buttocks; the gastrointestinal tract – the stomach, intestines, bladder and/or urethra may be involved; and the upper airway – larynx and tongue causing upper airway obstruction that may be life- threatening. Triggers vary and may include anxiety, surgery, medications and illnesses. Attacks often begin in childhood or adolescence, and may involve a combination of body areas, symptoms go away on their own, usually lasting 2 to 4 days. Causes of the attacks vary but can include physical or emotional stress and dental procedures. The most common form of the disorder is hereditary angioedema type 1, which is the result of a deficiency in of the C1 esterase inhibitors (complements) in the blood. Hereditary angioedema type II, is uncommon and is due to a dysfunction of the C1 inhibitor protein. A third type is called HAE with normal C1 inhibitor and usually begins in adulthood.

Other names for hereditary angioedema include: C1 esterase inhibitor deficiency, complement component C1 regulatory component deficiency, HAE, HANE, Hereditary angioneurotic edema, C1-INH, C1NH.

Hereditary Angioedema Resources
Medication & Financial Assistance Resources
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