Primary Immunodeficiency

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Approved and Donation Ready

This fund has been developed in response to patients who have contacted PAF for help with their medication expenses and could not find help. While this fund has been fully designed and we are ready to provide needed support to these patient communities, this fund is not yet able to accept applications for assistance as we are still working to secure charitable donations that will allow us to open it.

If you, or someone you know, would like to contribute to this fund, please visit our Donors page for more information on how to provide critical support for patients in need.

Fund Type

Co-Pay, Co-insurance & Deductible (medications and office visits) & Medical Insurance Premiums

Maximum Award Level

$12,000 Per Year

Eligibility Requirements
  • Household Income Requirements 400% or less of Federal Poverty Guideline (FPG) (adjusted for Cost of Living Index (COLI) and number in household)
  • Insurance Requirements All Insurance Types
  • Must reside and receive treatment in the United States.

About Primary Immunodeficiency

Primary immunodeficiency diseases (PIDDs) — also called primary immune disorders or primary immunodeficiency, are a group of more than 350 rare hereditary or genetic disorders that impair the immune system. Without a functional immune response, antibodies that are produced in response to infection are missing, subjecting people to chronic, debilitating infections. Depending on the disease severity, these conditions may be diagnosed in infancy, childhood or adulthood. About 60% of people with primary immunodeficiency disorders are male. Problems with B cells are the most common PIDD, accounting for more than half of all disorders.

There are two types of immunodeficiency: the primary or congenital form is caused by a genetic defect in one of several essential genes involved in the immune response; while acquired or secondary immunodeficiency occurs when the immune system is compromised due to an environmental factor.

Types of PIDD include Selective IgA Deficiency is the most common PIDD, this disorder has absent level of a blood protein called immunoglobulin A (IgA); Common variable immunodeficiency (CVID), leaves the immune system unable to defend against severe infections affecting the ears, sinuses and respiratory tract. DiGeorge’s Syndrome (DGS) is associated with decreased T cell production due to poorly developed thymus. Combined immune deficiency (SCID) is when there is a combined absence of T-lymphocyte and B-lymphocyte function; X-Linked Agammaglobulinemia (XLA or Bruton’s Agammaglobulinemia), prevents B cells from developing normally.

Primary Immunodeficiency Resources
Medication & Financial Assistance Resources
The Patient Advocate Foundation's (PAF) Co-Pay Relief (CPR) Program does not review the information contained on the website links provided for content, accuracy or completeness. Use of and access to this information is subject to the terms, limitations and conditions as outlined on the accessed websites. PAF Co-Pay Relief Program makes no representation as to the accuracy or any other aspect of the information contained on any website accessed from the CPR website, nor does PAF Co-Pay Relief Program necessarily endorse the website information provided. The information presented on the PAF Co-Pay Relief website is provided for general information only and is not intended as a substitute for medical care. Please talk with your healthcare provider about any information you acquire from this or any other website accessed through the PAF Co-Pay Relief program website.